Serma 5mg

$49.00

99%+ Purity

A 29-amino acid GHRH(1-29) fragment retaining full receptor activity, studied for somatotroph signaling and growth hormone secretion in pituitary research.

Verified test results

Every batch, independently tested.

Each lot is analysed by a third-party laboratory. The results below are from the certificate for this exact lot — not a representative sample.

ParameterResultMethodSpecification
IdentitySerma · PassUPLC/MSConfirmed
AppearanceWhite lyophilized powderVisualMeets spec
Purity99.05% · PassUPLC/MS> 98%
Net peptide content4.69 mgUPLC/MS5 mg

Lot PATX-SERM-2601-001 · analysed January 26, 2026 · Horizon Analytical

No endotoxin report is available for this lot.

Serma 5mg

Certificate of Analysis

Third-party tested for purity

5 mgLatest
Lot PATX-SERM-2601-001
99.05%
UPLC/MS purity · meets > 98%
Labeled
5 mg
Measured
4.69 mg
Identity
Confirmed
Tested Jan 26, 2026No endotoxin report is available for this lot.

Research Overview

Serma is the shortest bioactive fragment of growth hormone-releasing hormone (GHRH), consisting of the first 29 amino acids of the native 44-amino acid sequence. This truncated analog retains full GHRH receptor binding activity and stimulates growth hormone release from anterior pituitary somatotroph cells through cAMP-dependent signaling pathways.

Researchers investigate Serma to study GHRH receptor pharmacology, pituitary somatotroph function, and the GH-IGF-1 axis. Its relatively short half-life (compared to modified analogs like CJC (No Dac) and Tesa) makes it useful for studying acute GH pulse dynamics and receptor activation kinetics without the confounding effects of sustained receptor occupancy.

Serma serves as a foundational research tool in growth hormone research, providing a reference compound for characterizing the effects of structural modifications in newer GHRH analogs. Comparative studies examine how N-terminal modifications (Tesa), DAC conjugation (CJC (No Dac) with DAC), and other structural changes affect receptor binding affinity, signaling duration, and GH release profiles.

Laboratory applications include pituitary cell stimulation assays, GH secretion kinetics studies, receptor binding competition experiments, and structure-activity relationship analysis across the GHRH analog family.

Explore the PeptidesATX Research Library for additional peptide pharmacology guides and reference resources.

Frequently researched together

Compounds studied alongside this one

Frequently Asked Questions

What is Serma?
Serma is a synthetic peptide containing the first 29 amino acids of natural growth hormone-releasing hormone (GHRH). It is used in research studying the GH/IGF-1 axis and pituitary function.
Where can this research compound be purchased?
This compound is available at PeptidesATX (peptidesatx.com), a U.S.-based research peptide supplier in Austin, Texas. All orders include a Certificate of Analysis, same-day shipping Monday through Thursday, and free shipping on orders over $200.
Do you provide a Certificate of Analysis (COA)?
Yes. Every lot listed on this site has a Certificate of Analysis from an independent laboratory (Horizon Analytical). The certificate reports the compound’s identity and purity by UPLC/MS (specification >98%; every lot currently listed measured at or above 99.05%), the measured quantity against the labeled amount, and appearance. Most lots also have a separate endotoxin report. The certificates do not include heavy-metal, sterility, residual-solvent or microbial testing, so they are not evidence that a lot is free of every possible contaminant. Every certificate can be viewed on the COA page before purchasing.
How should I store this peptide?
Store lyophilized (powder) vials at −20°C or colder, dry and protected from light. This is general laboratory practice for lyophilized peptides; it is not based on a product-specific stability study. Once reconstituted, keep the solution refrigerated at 2–8°C, protected from light, and use it promptly — solutions are less stable than the powder, and how long one remains usable depends on the peptide, the diluent and handling. Avoid repeated freeze–thaw cycles.
How long does this peptide last after reconstitution?
We have not performed product-specific stability studies, so no fixed shelf life is claimed for a reconstituted solution. Keep it refrigerated at 2–8°C, protected from light, avoid freeze–thaw cycles, and use it promptly; discard any solution that turns cloudy or shows particles. Bacteriostatic water contains 0.9% benzyl alcohol as an antimicrobial preservative for multi-draw vials; the preservative does not slow chemical degradation of the peptide itself.
What is your shipping policy?
Standard same-day shipping is $7.99 on all orders placed before 4 PM CT, Monday through Thursday. Orders of $200 or more ship free. All orders ship from Austin, TX with tracking provided. We ship to all 50 US states.

All products currently listed on this site are for research purposes only. U.S. sourced. Not intended for human dosing, injection, or ingestion.