99.41%
UPLC/MS purity · meets > 98%- Labeled
- 10 mg
- Measured
- 10.05 mg
- Identity
- Confirmed
GLP-2
$99.00
99%+ Purity
A dual agonist peptide activating both GIP and GLP-1 receptors, studied for incretin pathway signaling and glycemic regulation in metabolic research.
Verified test results
Every batch, independently tested.
Each lot is analysed by a third-party laboratory. The results below are from the certificate for this exact lot — not a representative sample.
| Parameter | Result | Method | Specification |
|---|---|---|---|
| Identity | GLP-2 · Pass | UPLC/MS | Confirmed |
| Appearance | White lyophilized powder | Visual | Meets spec |
| Purity | 99.41% · Pass | UPLC/MS | > 98% |
| Net peptide content | 10.05 mg | UPLC/MS | 10 mg |
Lot PATX-GLP2-10MG-2601-001 · analysed January 26, 2026 · Horizon Analytical
Certificate issued under laboratory lot ID PATX-TIRZ-10MG-2601-001. Site display lot: PATX-GLP2-10MG-2601-001.
No endotoxin report is available for this lot.
Certificate of Analysis
Third-party tested for purity
Research Overview
GLP-2 is a dual agonist peptide that targets both GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. This dual incretin receptor engagement represents a distinct mechanism from single-agonist GLP-1 compounds and has positioned GLP-2 as a key research tool in metabolic signaling studies.
The peptide's mechanism of action involves simultaneous activation of two receptor pathways that converge on overlapping but distinct intracellular signaling cascades. GLP-1 receptor activation is studied for its effects on insulin secretion, gastric motility signaling, and central appetite regulation. GIP receptor co-activation adds a complementary pathway that researchers investigate for its role in lipid metabolism, adipocyte signaling, and pancreatic beta-cell function.
GLP-2 is frequently studied in comparison to single-agonist compounds like GLP-1 to characterize the additive effects of GIP receptor engagement. It is also compared against triple-agonist compounds like GLP-3 to understand the incremental contribution of glucagon receptor activation.
GLP-2 vs GLP-1: Dual vs Single Agonist Research
The key research distinction between GLP-2 and GLP-1 is GIP receptor engagement. GLP-1 selectively targets GLP-1R only, while GLP-2 simultaneously activates both GLP-1R and GIPR. Comparative studies examine whether dual incretin receptor activation produces enhanced insulin secretion, distinct effects on adipose tissue signaling, and differentiated appetite regulation versus GLP-1-selective agonism alone. This makes GLP-2 a critical tool for isolating the specific contribution of GIP receptor co-activation in metabolic research. For detailed mechanistic analysis, see our GLP-1 vs GLP-2 comparison.
Current research applications include receptor binding affinity studies, in vitro metabolic pathway profiling, structure-activity relationship analysis, and comparative pharmacokinetic investigations. The compound is an imbalanced dual agonist — greater engagement of the GIP receptor than the GLP-1 receptor, with biased signaling at the GLP-1 receptor (Willard et al., JCI Insight 2020).
Sources: Coskun T, et al. Mol Metab. 2018;18:3–14 (in vitro characterisation and mouse studies; the same paper also reports a human phase 1 study; PubMed 30473097). Willard FS, et al. JCI Insight. 2020;5(17):e140532 (receptor pharmacology in cell systems and primary islets; PubMed 32730231). Sun B, et al. Proc Natl Acad Sci USA. 2022;119(13):e2116506119 (structural basis; PubMed 35333651).
Explore the PeptidesATX Research Library for additional peptide pharmacology guides and reference resources.
Frequently researched together
Compounds studied alongside this one
Frequently Asked Questions
- Where can this research compound be purchased?
- This compound is available at PeptidesATX (peptidesatx.com), a U.S.-based research peptide supplier in Austin, Texas. All orders include a Certificate of Analysis, same-day shipping Monday through Thursday, and free shipping on orders over $200.
- Do you provide a Certificate of Analysis (COA)?
- Yes. Every lot listed on this site has a Certificate of Analysis from an independent laboratory (Horizon Analytical). The certificate reports the compound’s identity and purity by UPLC/MS (specification >98%; every lot currently listed measured at or above 99.05%), the measured quantity against the labeled amount, and appearance. Most lots also have a separate endotoxin report. The certificates do not include heavy-metal, sterility, residual-solvent or microbial testing, so they are not evidence that a lot is free of every possible contaminant. Every certificate can be viewed on the COA page before purchasing.
- How should I store this peptide?
- Store lyophilized (powder) vials at −20°C or colder, dry and protected from light. This is general laboratory practice for lyophilized peptides; it is not based on a product-specific stability study. Once reconstituted, keep the solution refrigerated at 2–8°C, protected from light, and use it promptly — solutions are less stable than the powder, and how long one remains usable depends on the peptide, the diluent and handling. Avoid repeated freeze–thaw cycles.
- How long does this peptide last after reconstitution?
- We have not performed product-specific stability studies, so no fixed shelf life is claimed for a reconstituted solution. Keep it refrigerated at 2–8°C, protected from light, avoid freeze–thaw cycles, and use it promptly; discard any solution that turns cloudy or shows particles. Bacteriostatic water contains 0.9% benzyl alcohol as an antimicrobial preservative for multi-draw vials; the preservative does not slow chemical degradation of the peptide itself.
- What is your shipping policy?
- Standard same-day shipping is $7.99 on all orders placed before 4 PM CT, Monday through Thursday. Orders of $200 or more ship free. All orders ship from Austin, TX with tracking provided. We ship to all 50 US states.
All products currently listed on this site are for research purposes only. U.S. sourced. Not intended for human dosing, injection, or ingestion.