Selank

Frequently Asked Questions

What is Selank?

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) derived from the endogenous immunomodulatory tetrapeptide tuftsin. A Pro-Gly-Pro C-terminal extension confers resistance to enzymatic degradation, dramatically extending its experimental half-life relative to native tuftsin. It was developed at the Russian Academy of Sciences’ Institute of Molecular Genetics.

What pathways does Selank engage?

Selank is multi-system: it inhibits enkephalin-degrading enzymes (raising endogenous enkephalin tone), modulates GABAergic signaling and benzodiazepine-binding-site expression, up-regulates BDNF in hippocampal tissue, and influences serotonergic and noradrenergic neurotransmission. It also has documented IL-6, IFN-γ, and TNF-α pathway effects in immunomodulatory research.

How is Selank different from Semx?

Both are short Russian-developed regulatory peptides, but their structures and primary pathways differ. Selank is a tuftsin-derived heptapeptide with anxiolytic/immunomodulatory emphasis. Semx is an ACTH(4-10)-derived heptapeptide with neurotrophic/BDNF emphasis. They are often studied together for complementary cognitive and stress-response pathway research.

How does Selank differ from native tuftsin in stability?

Selank carries a Pro-Gly-Pro extension at the C-terminus of the tuftsin sequence. In the published work this extension confers resistance to enzymatic degradation, giving Selank a substantially longer experimental half-life than native tuftsin, which is degraded within minutes in plasma.

What size of Selank is available?

PeptidesATX offers Selank in 10mg lyophilized vials. Each vial includes a Certificate of Analysis confirming ≥98% purity by HPLC.

Where can this research compound be purchased?

This compound is available at PeptidesATX (peptidesatx.com), a U.S.-based research peptide supplier in Austin, Texas. All orders include a Certificate of Analysis, same-day shipping Monday through Thursday, and free shipping on orders over $200.

Do you provide a Certificate of Analysis (COA)?

Yes. Every lot listed on this site has a Certificate of Analysis from an independent laboratory (Horizon Analytical). The certificate reports the compound’s identity and purity by UPLC/MS (specification >98%; every lot currently listed measured at or above 99.05%), the measured quantity against the labeled amount, and appearance. Most lots also have a separate endotoxin report. The certificates do not include heavy-metal, sterility, residual-solvent or microbial testing, so they are not evidence that a lot is free of every possible contaminant. Every certificate can be viewed on the COA page before purchasing.

How should I store this peptide?

Store lyophilized (powder) vials at −20°C or colder, dry and protected from light. This is general laboratory practice for lyophilized peptides; it is not based on a product-specific stability study. Once reconstituted, keep the solution refrigerated at 2–8°C, protected from light, and use it promptly — solutions are less stable than the powder, and how long one remains usable depends on the peptide, the diluent and handling. Avoid repeated freeze–thaw cycles.

How long does this peptide last after reconstitution?

We have not performed product-specific stability studies, so no fixed shelf life is claimed for a reconstituted solution. Keep it refrigerated at 2–8°C, protected from light, avoid freeze–thaw cycles, and use it promptly; discard any solution that turns cloudy or shows particles. Bacteriostatic water contains 0.9% benzyl alcohol as an antimicrobial preservative for multi-draw vials; the preservative does not slow chemical degradation of the peptide itself.

What is your shipping policy?

Standard same-day shipping is $7.99 on all orders placed before 4 PM CT, Monday through Thursday. Orders of $200 or more ship free. All orders ship from Austin, TX with tracking provided. We ship to all 50 US states.