99.37%
UPLC/MS purity · meets > 98%- Labeled
- 10 mg
- Measured
- 10.04 mg
- Identity
- Confirmed
- Endotoxin
- < 0.05 EU/mL
Semx 10mg
$45.00
99%+ Purity
A heptapeptide ACTH(4-10) analog with a Pro-Gly-Pro stability extension, studied for BDNF expression, neurotrophic factor signaling, and cognitive pathway research.
Verified test results
Every batch, independently tested.
Each lot is analysed by a third-party laboratory. The results below are from the certificate for this exact lot — not a representative sample.
| Parameter | Result | Method | Specification |
|---|---|---|---|
| Identity | Semx · Pass | UPLC/MS | Confirmed |
| Appearance | White lyophilized powder | Visual | Meets spec |
| Purity | 99.37% · Pass | UPLC/MS | > 98% |
| Net peptide content | 10.04 mg | UPLC/MS | 10 mg |
| Endotoxin | < 0.05 EU/mL | Endotoxin test | Reported |
Lot DPS-7737418 · analysed August 28, 2026 · Horizon Analytical
Certificate of Analysis
Third-party tested for purity
99.18%
UPLC/MS purity · meets > 98%- Labeled
- 10 mg
- Measured
- 9.8 mg
- Identity
- Confirmed
99.15%
UPLC/MS purity · meets > 98%- Labeled
- 10 mg
- Measured
- 10.34 mg
- Identity
- Confirmed
Research Overview
Semx is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-10), with a Pro-Gly-Pro tripeptide extension at the C-terminus that enhances metabolic stability. This structural modification significantly extends the peptide's functional half-life while retaining the neurotrophic properties associated with the ACTH(4-10) fragment, without the adrenal steroidogenic activity of full-length ACTH.
Researchers investigate Semx for its interactions with neurotrophic signaling pathways, particularly its effects on brain-derived neurotrophic factor (BDNF) expression, nerve growth factor (NGF) modulation, and TrkB receptor signaling. The peptide is studied as a pharmacological tool for understanding melanocortin receptor-independent neuropeptide signaling — a mechanism distinct from most melanocortin system agonists.
Semx's nootropic research profile centers on its documented effects on gene expression in neural tissue, where it modulates over 100 genes involved in neurotransmitter signaling, immune regulation, and vascular function. These broad transcriptomic effects make it a useful probe for studying peptide-mediated gene regulation in neuronal cell culture systems.
Laboratory applications include neurotrophic factor expression studies, neuronal cell viability assays, cognitive pathway modeling, and comparative pharmacology research against other ACTH-derived peptides. Semx is available in 10mg vials for laboratory investigation.
Explore the PeptidesATX Research Library for additional peptide pharmacology guides and reference resources.
Frequently researched together
Compounds studied alongside this one
Frequently Asked Questions
- Where can this research compound be purchased?
- This compound is available at PeptidesATX (peptidesatx.com), a U.S.-based research peptide supplier in Austin, Texas. All orders include a Certificate of Analysis, same-day shipping Monday through Thursday, and free shipping on orders over $200.
- Do you provide a Certificate of Analysis (COA)?
- Yes. Every lot listed on this site has a Certificate of Analysis from an independent laboratory (Horizon Analytical). The certificate reports the compound’s identity and purity by UPLC/MS (specification >98%; every lot currently listed measured at or above 99.05%), the measured quantity against the labeled amount, and appearance. Most lots also have a separate endotoxin report. The certificates do not include heavy-metal, sterility, residual-solvent or microbial testing, so they are not evidence that a lot is free of every possible contaminant. Every certificate can be viewed on the COA page before purchasing.
- How should I store this peptide?
- Store lyophilized (powder) vials at −20°C or colder, dry and protected from light. This is general laboratory practice for lyophilized peptides; it is not based on a product-specific stability study. Once reconstituted, keep the solution refrigerated at 2–8°C, protected from light, and use it promptly — solutions are less stable than the powder, and how long one remains usable depends on the peptide, the diluent and handling. Avoid repeated freeze–thaw cycles.
- How long does this peptide last after reconstitution?
- We have not performed product-specific stability studies, so no fixed shelf life is claimed for a reconstituted solution. Keep it refrigerated at 2–8°C, protected from light, avoid freeze–thaw cycles, and use it promptly; discard any solution that turns cloudy or shows particles. Bacteriostatic water contains 0.9% benzyl alcohol as an antimicrobial preservative for multi-draw vials; the preservative does not slow chemical degradation of the peptide itself.
- What is your shipping policy?
- Standard same-day shipping is $7.99 on all orders placed before 4 PM CT, Monday through Thursday. Orders of $200 or more ship free. All orders ship from Austin, TX with tracking provided. We ship to all 50 US states.
All products currently listed on this site are for research purposes only. U.S. sourced. Not intended for human dosing, injection, or ingestion.